Minato Sahashi, a struggling yet smart youngster, has failed his college admission tests for the second time, rendering him useless in the eyes of others around him. However, when a beautiful, magical woman descends from the sky and into his life, the direction of his seemingly grim destiny is significantly altered. Musubi is a one-of-a-kind entity known as a "Sekirei," a humanoid extraterrestrial with amazing talents. These aliens are notorious for kissing people who have the Ashikabi gene in order to unlock further dormant powers deep inside.