The seal that had been imprisoning the fallen angels, Kirin no Yuda and Houou no Ruka, is shattered, and the two seek to exact revenge on the God who had sent them to Hell by destroying the Heavens that were once their home. The Earth's guardian angels begin to vanish, and no one in Heaven can explain what is occurring. However, there is a strong suspicion of a malevolent animal spirit at work, and the four Saint Beasts are summoned to investigate.