The apparently endless cat-and-mouse game has concluded, and everyone is now living in peace. One day, an Eto-musume (Zodiac girl) named Na-tan comes, much to the surprise of the 12 signs and much to the happiness of Nya-tan (whose spirits are always lifted by the pure, straightforward Na-tan). Meanwhile, Chu-tan comes and forewarns of impending tragedy. "The seal... has been shattered." Who is the enigmatic Eto-musume Na-tan? What exactly is the deity that has risen behind the seal?