The powers of evil are rising. When the wicked genius Sister Jill changes one of her students into the bestial Breast Claw and dispatches her henchmen on a mission involving the gang Panther Claw and a jewelry shop theft, Honey Kisaragi leaves her Catholic girls' school as Cutie Honey to fight the menace. Sister Jill, on the other hand, seeks Honey's Airborne Element Fixing Device, which allows her to morph into one of Honey's seven various forms. Meanwhile, Sister Jill appears on the scene disguised as Inspector Genet, attempting to gain Honey's trust from a new aspect.