According to the Quirk Doomsday Theory teachings, the ideological organization Humarise believes that all persons with oddities are unhealthy and must be eliminated. To reconstruct the world, the fanatics of the group have created a devastating gadget known as a "Trigger Bomb," which causes individuals with peculiarities to lose control and die. Their commander, Flect Turn, manages to elude arrest by the Pro Heroes stationed across the planet. Izuku "Deku" Midoriya is accused of a crime he did not commit while working in the country of Otheon with Japan's number one Pro Hero. Deku soon finds himself on the run with the youngster after inadvertently implicating Roddy Soul, a local. Rody, Deku, and Deku's classmates must now stop the Trigger Bomb.